A novel and rapid method for obtaining high titre intact prion strains from mammalian brain

Mammalian prions exist as multiple strains which produce characteristic and highly reproducible phenotypes in defined hosts. How this strain diversity is encoded by a protein-only agent remains one of the most interesting and challenging questions in biology with wide relevance to understanding othe...

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Bibliographic Details
Main Authors: Wenborn, Adam, Terry, Cassandra, Gros, Nathalie, Joiner, Susan, D’Castro, Laura, Panico, Silvia, Sells, Jessica, Cronier, Sabrina, Linehan, Jacqueline M., Brandner, Sebastian, Saibil, Helen R., Collinge, John, Wadsworth, Jonathan D. F.
Format: Article
Language:English
Published: Nature Group Publishing 2015
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Online Access:https://repository.londonmet.ac.uk/3843/1/srep10062.pdf