Mice deficient in PAPP - a show resistance to the development of diabetic nephropathy

We investigated pregnancy-associated plasma protein-A (PAPP-A) in diabetic nephropathy. Normal human kidney showed specific staining for PAPP-A in glomeruli, and this staining was markedly increased in diabetic kidney. To assess the possible contribution of PAPP-A in the development of diabetic neph...

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Bibliographic Details
Main Authors: Mader, Jessica R., Resch, Zachary T., McLean, Gary R., Mikkelsen, Jakob H., Oxvig, Claus, Marler, Ronald J., Conover, Cheryl A.
Format: Article
Language:English
Published: BioScientifica 2013
Subjects:
Online Access:https://repository.londonmet.ac.uk/652/1/index.html