Loss of NnT increases expression of oxidative phosphorylation complexes in C57BL/6J hearts

Nicotinamide nucleotide transhydrogenase (NNT) is a proton pump in the inner mitochondrial membrane that generates reducing equivalents in the form of NAPDH, which can be used for anabolic pathways or to remove reactive oxygen species (ROS). A number of studies have linked NNT dysfunction to cardiom...

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Bibliographic Details
Main Authors: Williams, Jack L., Hall, Charlotte L., Meimaridou, Eirini, Metherell, Louise A.
Format: Article
Language:English
Published: MDPI 2021
Subjects:
Online Access:https://repository.londonmet.ac.uk/6737/1/ijms-22-06101.pdf