Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function
Heat-induced hypo-hydration (hyperosmotic hypovolemia) can reduce prolonged skeletal muscle performance; however, the mechanisms are less well understood and the reported effects on all aspects of neuromuscular function and brief maximal contractions are inconsistent. Historically, a 4-6% reduction...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Springer
2022
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| Online Access: | https://repository.londonmet.ac.uk/7443/1/Uddin2022_Article_CorticospinalAndPeripheralResp.pdf |
| _version_ | 1804072762532167680 |
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| author | Uddin, Nasir Tallent, Jamie Patterson, Stephen D. Goodall, Stuart Waldron, Mark |
| author_facet | Uddin, Nasir Tallent, Jamie Patterson, Stephen D. Goodall, Stuart Waldron, Mark |
| author_sort | Uddin, Nasir |
| collection | LMU |
| description | Heat-induced hypo-hydration (hyperosmotic hypovolemia) can reduce prolonged skeletal muscle performance; however, the mechanisms are less well understood and the reported effects on all aspects of neuromuscular function and brief maximal contractions are inconsistent. Historically, a 4-6% reduction of body mass has not been considered to impair muscle function in humans, as determined by muscle torque, membrane excitability and peak power production. With the development of magnetic resonance imaging and neurophysiological techniques, such as electromyography, peripheral nerve, and transcranial magnetic stimulation (TMS), the integrity of the brain-to-muscle pathway can be further investigated. The findings of this review demonstrate that heat-induced hypo-hydration impairs neuromuscular function, particularly during repeated and sustained contractions. Additionally, the mechanisms are separate to those of hyperthermia-induced fatigue and are likely a result of modulations to corticospinal inhibition, increased fibre conduction velocity, pain perception and impaired contractile function. This review also sheds light on the view that hypo-hydration has 'no effect' on neuromuscular function during brief maximal voluntary contractions. It is hypothesised that irrespective of unchanged force, compensatory reductions in cortical inhibition are likely to occur, in the attempt of achieving adequate force production. Studies using single-pulse TMS have shown that hypo-hydration can reduce maximal isometric and eccentric force, despite a reduction in cortical inhibition, but the cause of this is currently unclear. Future work should investigate the intracortical inhibitory and excitatory pathways within the brain, to elucidate the role of the central nervous system in force output, following heat-induced hypo-hydration. [Abstract copyright: © 2022. The Author(s).] |
| first_indexed | 2024-07-09T04:04:18Z |
| format | Article |
| id | oai:repository.londonmet.ac.uk:7443 |
| institution | London Metropolitan University |
| language | English |
| last_indexed | 2024-07-09T04:04:18Z |
| publishDate | 2022 |
| publisher | Springer |
| record_format | eprints |
| spelling | oai:repository.londonmet.ac.uk:74432022-08-12T10:21:27Z http://repository.londonmet.ac.uk/7443/ Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function Uddin, Nasir Tallent, Jamie Patterson, Stephen D. Goodall, Stuart Waldron, Mark 610 Medicine & health Heat-induced hypo-hydration (hyperosmotic hypovolemia) can reduce prolonged skeletal muscle performance; however, the mechanisms are less well understood and the reported effects on all aspects of neuromuscular function and brief maximal contractions are inconsistent. Historically, a 4-6% reduction of body mass has not been considered to impair muscle function in humans, as determined by muscle torque, membrane excitability and peak power production. With the development of magnetic resonance imaging and neurophysiological techniques, such as electromyography, peripheral nerve, and transcranial magnetic stimulation (TMS), the integrity of the brain-to-muscle pathway can be further investigated. The findings of this review demonstrate that heat-induced hypo-hydration impairs neuromuscular function, particularly during repeated and sustained contractions. Additionally, the mechanisms are separate to those of hyperthermia-induced fatigue and are likely a result of modulations to corticospinal inhibition, increased fibre conduction velocity, pain perception and impaired contractile function. This review also sheds light on the view that hypo-hydration has 'no effect' on neuromuscular function during brief maximal voluntary contractions. It is hypothesised that irrespective of unchanged force, compensatory reductions in cortical inhibition are likely to occur, in the attempt of achieving adequate force production. Studies using single-pulse TMS have shown that hypo-hydration can reduce maximal isometric and eccentric force, despite a reduction in cortical inhibition, but the cause of this is currently unclear. Future work should investigate the intracortical inhibitory and excitatory pathways within the brain, to elucidate the role of the central nervous system in force output, following heat-induced hypo-hydration. [Abstract copyright: © 2022. The Author(s).] Springer 2022 Article PeerReviewed text en cc_by_4 https://repository.londonmet.ac.uk/7443/1/Uddin2022_Article_CorticospinalAndPeripheralResp.pdf Uddin, Nasir, Tallent, Jamie, Patterson, Stephen D., Goodall, Stuart and Waldron, Mark (2022) Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function. European journal of applied physiology, 122 (8). pp. 1797-1810. ISSN 1439-6327 https://doi.org/10.1007/s00421-022-04937-z 10.1007/s00421-022-04937-z |
| spellingShingle | 610 Medicine & health Uddin, Nasir Tallent, Jamie Patterson, Stephen D. Goodall, Stuart Waldron, Mark Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function |
| title | Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function |
| title_full | Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function |
| title_fullStr | Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function |
| title_full_unstemmed | Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function |
| title_short | Corticospinal and peripheral responses to heat-induced hypo-hydration: potential physiological mechanisms and implications for neuromuscular function |
| title_sort | corticospinal and peripheral responses to heat induced hypo hydration potential physiological mechanisms and implications for neuromuscular function |
| topic | 610 Medicine & health |
| url | https://repository.londonmet.ac.uk/7443/1/Uddin2022_Article_CorticospinalAndPeripheralResp.pdf |
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