Proteins behaving badly: the role of (hIAPP) in type 2 diabetes

Type 2 diabetes is a complex condition. It can result in complications that affect different parts of the body. Currently there is no cure, but there are treatments can manage the condition,although they are not perfect. Our understanding of the condition at the molecular level islimited. Here we su...

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Bibliographic Details
Main Authors: Terry, Cassandra, White, Kenneth, Hassan, Shahab, Sevcuka, Adriana
Format: Article
Language:English
English
Published: Research Outreach 2023
Subjects:
Online Access:https://repository.londonmet.ac.uk/8790/1/index.html
https://repository.londonmet.ac.uk/8790/2/ResearchOutreachhIAPPArticleSept2023.pdf
Description
Summary:Type 2 diabetes is a complex condition. It can result in complications that affect different parts of the body. Currently there is no cure, but there are treatments can manage the condition,although they are not perfect. Our understanding of the condition at the molecular level islimited. Here we summarise the important role of a protein called human Islet AmyloidPolypeptide (hIAPP) in sugar regulation and when it malfunctions, its role in type 2 diabetes.Understanding how this protein works may help with earlier diagnosis and the developmentof medications to manage the condition better. (Outreach article)