Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A

The synthesis of mono- and novel bis-methylated pyrrolo[1,2-a]quinoxalines through the addition of unstable methyl radicals to aryl isocyanides is described contingent upon the reaction conditions employed. The strategy has been effectively employed in the total synthesis of the natural product mari...

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Main Authors: Damai, Margarita, Guzzardi, Norman, Lewis, Viliyana, Rao, Zenobia X., Sykes, Daniel, Patel, Bhaven
Format: Article
Language:English
Published: Royal Society of Chemistry 2023
Subjects:
Online Access:https://repository.londonmet.ac.uk/8814/1/d3ra05952a.pdf
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author Damai, Margarita
Guzzardi, Norman
Lewis, Viliyana
Rao, Zenobia X.
Sykes, Daniel
Patel, Bhaven
author_facet Damai, Margarita
Guzzardi, Norman
Lewis, Viliyana
Rao, Zenobia X.
Sykes, Daniel
Patel, Bhaven
author_sort Damai, Margarita
collection LMU
description The synthesis of mono- and novel bis-methylated pyrrolo[1,2-a]quinoxalines through the addition of unstable methyl radicals to aryl isocyanides is described contingent upon the reaction conditions employed. The strategy has been effectively employed in the total synthesis of the natural product marinoquinoline A.
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spelling oai:repository.londonmet.ac.uk:88142023-10-30T15:16:10Z http://repository.londonmet.ac.uk/8814/ Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A Damai, Margarita Guzzardi, Norman Lewis, Viliyana Rao, Zenobia X. Sykes, Daniel Patel, Bhaven 540 Chemistry & allied sciences The synthesis of mono- and novel bis-methylated pyrrolo[1,2-a]quinoxalines through the addition of unstable methyl radicals to aryl isocyanides is described contingent upon the reaction conditions employed. The strategy has been effectively employed in the total synthesis of the natural product marinoquinoline A. Royal Society of Chemistry 2023-10-10 Article PeerReviewed text en cc_by_nc https://repository.londonmet.ac.uk/8814/1/d3ra05952a.pdf Damai, Margarita, Guzzardi, Norman, Lewis, Viliyana, Rao, Zenobia X., Sykes, Daniel and Patel, Bhaven (2023) Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A. RSC Advances, 13 (42). pp. 29561-29567. ISSN 2046-2069 https://pubs.rsc.org/en/content/articlelanding/2023/ra/d3ra05952a 10.1039/D3RA05952A
spellingShingle 540 Chemistry & allied sciences
Damai, Margarita
Guzzardi, Norman
Lewis, Viliyana
Rao, Zenobia X.
Sykes, Daniel
Patel, Bhaven
Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A
title Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A
title_full Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A
title_fullStr Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A
title_full_unstemmed Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A
title_short Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A
title_sort crafting mono and novel bis methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline a
topic 540 Chemistry & allied sciences
url https://repository.londonmet.ac.uk/8814/1/d3ra05952a.pdf
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