| Summary: | Industry 4.0 (I4.0) and Circular Economy (CE) are emerging in academic, managerial, and policy debates, leading to integrating sustainable supply chain and net zero paradigms as an important phenomenon for maintaining competitive advantages in business. Although CE and I4.0 have significant benefits, their integration is largely untapped, representing a significant opportunity to integrate technological advancements with sustainable practices. Hence, this study investigates how CE and I4.0 can be integrated to achieve net zero in a knowledge-based sustainable supply chain. As part of this objective, the paper conducts an exploratory systematic review of selected articles published in peer-reviewed journals. Three main categories are identified from the selected articles: (i) CE principles and I4.0 technologies integration, (ii) the role of CE-I4.0 nexus in a sustainable supply chain (iii) leveraging CE-4.0 integration for net zero sustainable supply chains. We propose a multi-perspective framework to analyze
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