Development of novel quantitative methods for monitoring neurodegeneratie phenotypes in Niemann-Pick disease type C mice

A hallmark of neurodegenerative diseases, such as the rare monogenic lysosomal storage disease, Niemann-Pick disease type C (NPC), is motor dysfunction. There- fore, gait analysis is frequently used in pre-clinical and clinical studies. The Catwalk system is an automated instrument that collects gai...

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Bibliographic Details
Main Author: Chen, HT
Other Authors: Platt, F
Format: Thesis
Language:English
Published: 2023
Subjects: