Development of novel quantitative methods for monitoring neurodegeneratie phenotypes in Niemann-Pick disease type C mice
A hallmark of neurodegenerative diseases, such as the rare monogenic lysosomal storage disease, Niemann-Pick disease type C (NPC), is motor dysfunction. There- fore, gait analysis is frequently used in pre-clinical and clinical studies. The Catwalk system is an automated instrument that collects gai...
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Format: | Thesis |
Language: | English |
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2023
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