Seroprevalence of toxoplasma gondii infection in refugee and migrant pregnant women along the Thailand–Myanmar border

Toxoplasma gondii primary infection in pregnancy is associated with poor obstetric outcomes. This study aimed to determine the seroprevalence of Toxoplasma infection in pregnant migrant and refugee women from Myanmar attending antenatal care in Thailand. A random selection of 199 residual blood samp...

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Bibliografische gegevens
Hoofdauteurs: van Enter, B, Lau, Y, Ling, C, Watthanaworawit, W, Sukthana, Y, Lee, W, Nosten, F, McGready, R
Formaat: Journal article
Gepubliceerd in: American Society of Tropical Medicine and Hygiene 2017
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author van Enter, B
Lau, Y
Ling, C
Watthanaworawit, W
Sukthana, Y
Lee, W
Nosten, F
McGready, R
author_facet van Enter, B
Lau, Y
Ling, C
Watthanaworawit, W
Sukthana, Y
Lee, W
Nosten, F
McGready, R
author_sort van Enter, B
collection OXFORD
description Toxoplasma gondii primary infection in pregnancy is associated with poor obstetric outcomes. This study aimed to determine the seroprevalence of Toxoplasma infection in pregnant migrant and refugee women from Myanmar attending antenatal care in Thailand. A random selection of 199 residual blood samples from first antenatal screen in 2014–2015 was tested for Toxoplasma IgG and IgM antibodies. Seroprevalence of Toxoplasma infection was 31.7% (95% confidence interval = 25.6–38.4). Avidity testing in the three positive IgM cases indicated all were past infections. Multiparity (≥ 3 children) was significantly associated with higher Toxoplasma seropositivity rates. Seroprevalence of T. gondii infection in this pregnant population is similar to the only other report from Myanmar, and was significantly associated with multiparity. Toxoplasma infection is important in pregnant women. Nevertheless, in this marginalized population, this infection may be given less priority, due to resource constraints in providing the most basic components of safe motherhood programs.
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spelling oxford-uuid:004aa75b-0e8f-4299-a084-c165b9b5702f2022-03-26T08:28:44ZSeroprevalence of toxoplasma gondii infection in refugee and migrant pregnant women along the Thailand–Myanmar borderJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:004aa75b-0e8f-4299-a084-c165b9b5702fSymplectic Elements at OxfordAmerican Society of Tropical Medicine and Hygiene2017van Enter, BLau, YLing, CWatthanaworawit, WSukthana, YLee, WNosten, FMcGready, RToxoplasma gondii primary infection in pregnancy is associated with poor obstetric outcomes. This study aimed to determine the seroprevalence of Toxoplasma infection in pregnant migrant and refugee women from Myanmar attending antenatal care in Thailand. A random selection of 199 residual blood samples from first antenatal screen in 2014–2015 was tested for Toxoplasma IgG and IgM antibodies. Seroprevalence of Toxoplasma infection was 31.7% (95% confidence interval = 25.6–38.4). Avidity testing in the three positive IgM cases indicated all were past infections. Multiparity (≥ 3 children) was significantly associated with higher Toxoplasma seropositivity rates. Seroprevalence of T. gondii infection in this pregnant population is similar to the only other report from Myanmar, and was significantly associated with multiparity. Toxoplasma infection is important in pregnant women. Nevertheless, in this marginalized population, this infection may be given less priority, due to resource constraints in providing the most basic components of safe motherhood programs.
spellingShingle van Enter, B
Lau, Y
Ling, C
Watthanaworawit, W
Sukthana, Y
Lee, W
Nosten, F
McGready, R
Seroprevalence of toxoplasma gondii infection in refugee and migrant pregnant women along the Thailand–Myanmar border
title Seroprevalence of toxoplasma gondii infection in refugee and migrant pregnant women along the Thailand–Myanmar border
title_full Seroprevalence of toxoplasma gondii infection in refugee and migrant pregnant women along the Thailand–Myanmar border
title_fullStr Seroprevalence of toxoplasma gondii infection in refugee and migrant pregnant women along the Thailand–Myanmar border
title_full_unstemmed Seroprevalence of toxoplasma gondii infection in refugee and migrant pregnant women along the Thailand–Myanmar border
title_short Seroprevalence of toxoplasma gondii infection in refugee and migrant pregnant women along the Thailand–Myanmar border
title_sort seroprevalence of toxoplasma gondii infection in refugee and migrant pregnant women along the thailand myanmar border
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