Aggrecanases and TIMP-3 in osteoarthritis: structure, function and in vivo challenges
Príomhchruthaitheoir: | Nagase, H |
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Formáid: | Journal article |
Foilsithe / Cruthaithe: |
2009
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Míreanna comhchosúla
Míreanna comhchosúla
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TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5).
de réir: Kashiwagi, M, et al.
Foilsithe / Cruthaithe: (2001) -
Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage
de réir: Troeberg, L, et al.
Foilsithe / Cruthaithe: (2009) -
TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors.
de réir: Gendron, C, et al.
Foilsithe / Cruthaithe: (2003) -
Calcium pentosan polysulfate increases affinity between aggrecanases (ADAMTS-4 and-5) and TIMP-3 by a conformational change
de réir: Troeberg, L, et al.
Foilsithe / Cruthaithe: (2010) -
Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis
de réir: Hiroyuki Nakamura, et al.
Foilsithe / Cruthaithe: (2020-06-01)