Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.

Genetic risk factors frequently affect multiple common human diseases, providing insight into shared pathophysiological pathways and opportunities for therapeutic development. However, systematic identification of genetic profiles of disease risk is limited by the availability of both comprehensive...

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Hlavní autoři: Cortes, A, Albers, PK, Dendrou, CA, Fugger, L, McVean, G
Médium: Journal article
Jazyk:English
Vydáno: Nature Research 2019