Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.

Genetic risk factors frequently affect multiple common human diseases, providing insight into shared pathophysiological pathways and opportunities for therapeutic development. However, systematic identification of genetic profiles of disease risk is limited by the availability of both comprehensive...

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Detalhes bibliográficos
Main Authors: Cortes, A, Albers, PK, Dendrou, CA, Fugger, L, McVean, G
Formato: Journal article
Idioma:English
Publicado em: Nature Research 2019