Interaction of the molecular chaperone alpha B-crystallin with alpha-synuclein: Effects on amyloid fibril formation and chaperone activity

Interaction of the molecular chaperone alpha B-crystallin with alpha-synuclein: Effects on amyloid fibril formation and chaperone activity

Diğer sürümleri göster (1)

α-Synuclein is a pre-synaptic protein, the function of which is not completely understood, but its pathological form is involved in neurodegenerative diseases. In vitro, α-synuclein spontaneously forms amyloid fibrils. Here, we report that αB-crystallin, a molecular chaperone found in Lewy bodies th...

Detaylı Bibliyografya
Asıl Yazarlar:	Rekas, A, Adda, C, Aquilina, J, Barnham, K, Sunde, M, Galatis, D, Williamson, N, Masters, C, Anders, R, Robinson, C, Cappai, R, Carver, J
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2004

Benzer Materyaller

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity.
Yazar:: Rekas, A, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Mimicking phosphorylation of alphaB-crystallin affects its chaperone activity.
Yazar:: Ecroyd, H, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human alphaA-, alphaB- and R120G alphaB-crystallins.
Yazar:: Meehan, S, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure.
Yazar:: Aquilina, J, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure.
Yazar:: Aquilina, J, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Polydispersity of a mammalian chaperone: mass spectrometry reveals the population of oligomers in alphaB-crystallin.
Yazar:: Aquilina, J, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Polydispersity of a mammalian chaperone: mass spectrometry reveals the population of oligomers in alphaB-crystallin
Yazar:: Aquilina, J, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

The interaction of the molecular chaperone alpha-crystallin with unfolding alpha-lactalbumin: a structural and kinetic spectroscopic study.
Yazar:: Carver, J, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Association of the chaperone alphaB-crystallin with titin in heart muscle.
Yazar:: Bullard, B, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

The characterization of human [gamma]D-crystallin mutants and their differential interactions with the lens chaperone [alpha]B-crystallin
Yazar:: Moreau, Kate L. (Kate Lauren)
Baskı/Yayın Bilgisi: (2011)

The quaternary organization and dynamics of the molecular chaperone HSP26 are thermally regulated.
Yazar:: Benesch, J, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable.
Yazar:: Treweek, T, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Tsp36, a tapeworm small heat-shock protein with a duplicated alpha-crystallin domain, forms dimers and tetramers with good chaperone-like activity.
Yazar:: Kappé, G, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Chaperones /
Yazar:: Makarow, Marja, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

In vitro interactions of the small heat shock protein chaperone human [alpha]B-crystallin with its physiological substrates in the lens [gamma]-crystallins
Yazar:: Acosta-Sampson, Ligia I
Baskı/Yayın Bilgisi: (2011)

Release of frustration drives corneal amyloid disaggregation by brain chaperone
Yazar:: Low, Kimberly Jia Yi, ve diğerleri
Baskı/Yayın Bilgisi: (2023)

SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones
Yazar:: Donmez Yalcin, Gizem, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Watching and weighting--chaperone complexes in action.
Yazar:: Robinson, C
Baskı/Yayın Bilgisi: (2005)

The influence of the N-terminal region proximal to the core domain on the assembly and chaperone activity of αB-crystallin
Yazar:: Jovcevski, B, ve diğerleri
Baskı/Yayın Bilgisi: (2018)

The extracellular chaperone clusterin potently inhibits human lysozyme amyloid formation by interacting with prefibrillar species.
Yazar:: Kumita, JR, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs.
Yazar:: Phillips, J, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Evidence for chaperone function in mechanosensation
Yazar:: Collier, M, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

Distinct Prion Strains Are Defined by Amyloid Core Structure and Chaperone Binding Site Dynamics
Yazar:: Frederick, Kendra K., ve diğerleri
Baskı/Yayın Bilgisi: (2016)

Cross-system excision of chaperone-mediated proteolysis in chaperone-assisted recombinant protein production.
Yazar:: Martínez-Alonso, M, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Chaperoning viral protein evolution
Yazar:: Phillips, Angela Marie, Ph. D. Massachusetts Institute of Technology
Baskı/Yayın Bilgisi: (2018)

Molecular chaperones and cell signalling /
Yazar:: Henderson, Brian, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

DnaJ chaperones contribute to canalization
Yazar:: Hughes, S, ve diğerleri
Baskı/Yayın Bilgisi: (2019)

Amyloid fibril formation by an SH3 domain.
Yazar:: Guijarro, J, ve diğerleri
Baskı/Yayın Bilgisi: (1998)

Alpha-synuclein proximity ligation assay (AS-PLA) in brain sections to probe for alpha-synuclein oligomers
Yazar:: Roberts, RF, ve diğerleri
Baskı/Yayın Bilgisi: (2019)

Anticholinergic drugs interact with neuroprotective chaperone L-PGDS and modulate cytotoxicity of Aβ amyloids
Yazar:: Low, Kimberly Jia Yi, ve diğerleri
Baskı/Yayın Bilgisi: (2021)

Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies
Yazar:: Parkkinen, L, ve diğerleri
Baskı/Yayın Bilgisi: (2016)

The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity.
Yazar:: Hochberg, G, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Loss of chaperone protein in human cancer
Yazar:: Adighibe, O
Baskı/Yayın Bilgisi: (2012)

Physiological and pathological properties of alpha-synuclein.
Yazar:: Tofaris, G, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Amyloid β chaperone — lipocalin-type prostaglandin D synthase acts as a peroxidase in the presence of heme
Yazar:: Phillips, Margaret, ve diğerleri
Baskı/Yayın Bilgisi: (2022)

Molecular basis of amyloid-β chaperone activity of lipocalin-type prostaglandin D synthase (L-PGDS)
Yazar:: Kannaian, Bhuvaneswari
Baskı/Yayın Bilgisi: (2020)

From molecular chaperones to membrane motors: through the lens of a mass spectrometrist
Yazar:: Robinson, C
Baskı/Yayın Bilgisi: (2017)

Subunit exchange of polydisperse proteins: mass spectrometry reveals consequences of alphaA-crystallin truncation
Yazar:: Aquilina, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Mass spectrometry quantifies protein interactions--from molecular chaperones to membrane porins.
Yazar:: Hopper, J, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Characterization of the oligomeric states of insulin in self-assembly and amyloid fibril formation by mass spectrometry.
Yazar:: Nettleton, E, ve diğerleri
Baskı/Yayın Bilgisi: (2000)