Serial cryoFIB/SEM reveals cytoarchitectural disruptions in Leigh syndrome patient cells
The advancement of serial cryoFIB/SEM offers an opportunity to study large volumes of near-native, fully hydrated frozen cells and tissues at voxel sizes of 10 nm and below. We explored this capability for pathologic characterization of vitrified human patient cells by developing and optimi...
| Hoofdauteurs: | , , , , , , , , , , |
|---|---|
| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
Cell Press
2020
|