Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery.

Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery.

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BACKGROUND: New vaccines to prevent tuberculosis are urgently needed. MVA85A is a novel viral vector TB vaccine candidate designed to boost BCG-induced immunity when delivered intradermally. To date, intramuscular delivery has not been evaluated. Skin and muscle have distinct anatomical and immunolo...

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Hauptverfasser:	Meyer, J, Harris, SA, Satti, I, Poulton, I, Poyntz, H, Tanner, R, Rowland, R, Griffiths, K, Fletcher, H, Mcshane, H
Format:	Journal article
Sprache:	English
Veröffentlicht:	2013

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