Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery.
BACKGROUND: New vaccines to prevent tuberculosis are urgently needed. MVA85A is a novel viral vector TB vaccine candidate designed to boost BCG-induced immunity when delivered intradermally. To date, intramuscular delivery has not been evaluated. Skin and muscle have distinct anatomical and immunolo...
Главные авторы: | Meyer, J, Harris, SA, Satti, I, Poulton, I, Poyntz, H, Tanner, R, Rowland, R, Griffiths, K, Fletcher, H, Mcshane, H |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
2013
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