P2X6 knockout mice exhibit normal electrolyte homeostasis
ATP-mediated signaling is an important regulator of electrolyte transport in the kidney. The purinergic cation channel P2X6 has been previously localized to the distal convoluted tubule (DCT), a nephron segment important for Mg2+ and Na+ reabsorption, but its role in ion transport remains unknown. I...
Main Authors: | De Baaij, J, Kompatscher, A, Viering, D, Bos, C, Bindels, R, Hoenderop, J |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2016
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