P2X6 knockout mice exhibit normal electrolyte homeostasis

ATP-mediated signaling is an important regulator of electrolyte transport in the kidney. The purinergic cation channel P2X6 has been previously localized to the distal convoluted tubule (DCT), a nephron segment important for Mg2+ and Na+ reabsorption, but its role in ion transport remains unknown. I...

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Bibliographic Details
Main Authors: De Baaij, J, Kompatscher, A, Viering, D, Bos, C, Bindels, R, Hoenderop, J
Format: Journal article
Language:English
Published: Public Library of Science 2016

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