Pulmonary outcome in former preterm, very low birth weight children with bronchopulmonary dysplasia: A case-control follow-up at school age
Objective To assess and compare long-term pulmonary outcomes in former preterm-born, very low birth weight (VLBW) children with and without bronchopulmonary dysplasia (BPD) born in the surfactant era. Study design Pulmonary function tests (ie, spirometry, body plethysmography, and gas transfer testi...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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2014
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| _version_ | 1797050346552426496 |
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| author | Vom Hove, M Prenzel, F Uhlig, H Robel-Tillig, E |
| author_facet | Vom Hove, M Prenzel, F Uhlig, H Robel-Tillig, E |
| author_sort | Vom Hove, M |
| collection | OXFORD |
| description | Objective To assess and compare long-term pulmonary outcomes in former preterm-born, very low birth weight (VLBW) children with and without bronchopulmonary dysplasia (BPD) born in the surfactant era. Study design Pulmonary function tests (ie, spirometry, body plethysmography, and gas transfer testing) were performed in children with a history of VLBW and BPD (n = 28) and compared with a matched preterm-born VLBW control group (n = 28). Medical history was evaluated by questionnaire. Results At time of follow-up (mean age, 9.5 years), respiratory symptoms (36% vs 8%) and receipt of asthma medication (21% vs 0%) were significantly more frequent in the preterm-born children with previous BPD than in those with no history of BPD. The children with a history of BPD had significantly lower values for forced expiratory volume in 1 second (z-score -1.27 vs -0.4; P =.008), forced vital capacity (z-score -1.39 vs -0.71 z-score; P =.022), and forced expiratory flow rate at 50% of forced vital capacity (z-score -2.21 vs -1.04; P =.048) compared with the preterm control group. Conclusion Preterm-born children with a history of BPD are significantly more likely to have lung function abnormalities, such as airway obstruction and respiratory symptoms, at school age compared with preterm-born children without BPD. © Copyright 2014 Mosby Inc. All rights reserved. |
| first_indexed | 2024-03-06T18:03:46Z |
| format | Journal article |
| id | oxford-uuid:00b7cea2-c03d-48c6-ba00-e335f0ef9b08 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:03:46Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | oxford-uuid:00b7cea2-c03d-48c6-ba00-e335f0ef9b082022-03-26T08:30:59ZPulmonary outcome in former preterm, very low birth weight children with bronchopulmonary dysplasia: A case-control follow-up at school ageJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:00b7cea2-c03d-48c6-ba00-e335f0ef9b08EnglishSymplectic Elements at Oxford2014Vom Hove, MPrenzel, FUhlig, HRobel-Tillig, EObjective To assess and compare long-term pulmonary outcomes in former preterm-born, very low birth weight (VLBW) children with and without bronchopulmonary dysplasia (BPD) born in the surfactant era. Study design Pulmonary function tests (ie, spirometry, body plethysmography, and gas transfer testing) were performed in children with a history of VLBW and BPD (n = 28) and compared with a matched preterm-born VLBW control group (n = 28). Medical history was evaluated by questionnaire. Results At time of follow-up (mean age, 9.5 years), respiratory symptoms (36% vs 8%) and receipt of asthma medication (21% vs 0%) were significantly more frequent in the preterm-born children with previous BPD than in those with no history of BPD. The children with a history of BPD had significantly lower values for forced expiratory volume in 1 second (z-score -1.27 vs -0.4; P =.008), forced vital capacity (z-score -1.39 vs -0.71 z-score; P =.022), and forced expiratory flow rate at 50% of forced vital capacity (z-score -2.21 vs -1.04; P =.048) compared with the preterm control group. Conclusion Preterm-born children with a history of BPD are significantly more likely to have lung function abnormalities, such as airway obstruction and respiratory symptoms, at school age compared with preterm-born children without BPD. © Copyright 2014 Mosby Inc. All rights reserved. |
| spellingShingle | Vom Hove, M Prenzel, F Uhlig, H Robel-Tillig, E Pulmonary outcome in former preterm, very low birth weight children with bronchopulmonary dysplasia: A case-control follow-up at school age |
| title | Pulmonary outcome in former preterm, very low birth weight children with bronchopulmonary dysplasia: A case-control follow-up at school age |
| title_full | Pulmonary outcome in former preterm, very low birth weight children with bronchopulmonary dysplasia: A case-control follow-up at school age |
| title_fullStr | Pulmonary outcome in former preterm, very low birth weight children with bronchopulmonary dysplasia: A case-control follow-up at school age |
| title_full_unstemmed | Pulmonary outcome in former preterm, very low birth weight children with bronchopulmonary dysplasia: A case-control follow-up at school age |
| title_short | Pulmonary outcome in former preterm, very low birth weight children with bronchopulmonary dysplasia: A case-control follow-up at school age |
| title_sort | pulmonary outcome in former preterm very low birth weight children with bronchopulmonary dysplasia a case control follow up at school age |
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