Stochastic loss and gain of symmetric divisions in the C. elegans epidermis perturbs robustness of stem cell number

Biological systems are subject to inherent stochasticity. Nevertheless, development is remarkably robust, ensuring the consistency of key phenotypic traits such as correct cell numbers in a certain tissue. It is currently unclear which genes modulate phenotypic variability, what their relationship i...

詳細記述

書誌詳細
主要な著者: Katsanos, D, Koneru, S, Mestek Boukhibar, L, Gritti, N, Ghose, R, Appleford, P, Doitsidou, M, Woollard, A, Van Zon, J, Poole, R, Barkoulas, M
フォーマット: Journal article
言語:English
出版事項: Public Library of Science 2017