Epigenetic gene promoter methylation at birth is associated with child's later adiposity.
OBJECTIVE: Fixed genomic variation explains only a small proportion of the risk of adiposity. In animal models, maternal diet alters offspring body composition, accompanied by epigenetic changes in metabolic control genes. Little is known about whether such processes operate in humans. RESEARCH DESI...
Hlavní autoři: | Godfrey, K, Sheppard, A, Gluckman, P, Lillycrop, K, Burdge, G, McLean, C, Rodford, J, Slater-Jefferies, J, Garratt, E, Crozier, SR, Emerald, B, Gale, C, Inskip, H, Cooper, C, Hanson, M |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2011
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