Assembly of the oligomeric membrane pore formed by Staphylococcal alpha-hemolysin examined by truncation mutagenesis.

The alpha-hemolysin (alpha HL) from Staphylococcus aureus causes the lysis of susceptible cells such as rabbit erythrocytes (rRBCs). Lysis is associated with the formation of a hexameric pore in the plasma membrane. Here we show that truncation mutants of alpha HL missing 2 to 22 N-terminal amino ac...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Walker, B, Krishnasastry, M, Zorn, L, Bayley, J
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 1992

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