MRI as an outcome in multiple sclerosis clinical trials.

MRI as an outcome in multiple sclerosis clinical trials.

INTRODUCTION: T2-weighted and gadolinium enhanced T1-weighted MRI scans measure plaque burden and breakdown of the blood-brain barrier, respectively, in multiple sclerosis (MS) lesions. These have become widely used outcome measures for monitoring disease activity in clinical trials and clinical pr...

Полное описание

Библиографические подробности
Главные авторы:	Daumer, M, Neuhaus, A, Morrissey, S, Hintzen, R, Ebers, G
Формат:	Journal article
Язык:	English
Опубликовано:	2009

Схожие документы

MRI ASANOUTCOMEIN MULTIPLE SCLEROSIS CLINICAL TRIALS Reply
по: Ebers, G, и др.
Опубликовано: (2009)

Early relapses, onset of progression, and late outcome in multiple sclerosis.
по: Scalfari, A, и др.
Опубликовано: (2013)

Age and disability accumulation in multiple sclerosis.
по: Scalfari, A, и др.
Опубликовано: (2011)

The genetics of clinical outcome in multiple sclerosis.
по: Ramagopalan, S, и др.
Опубликовано: (2008)

Onset of secondary progressive phase and long-term evolution of multiple sclerosis.
по: Scalfari, A, и др.
Опубликовано: (2014)

Disability as an outcome in MS clinical trials.
по: Ebers, G, и др.
Опубликовано: (2008)

Mutations in the hemochromatosis gene and the clinical outcome of multiple sclerosis.
по: Ramagopalan, S, и др.
Опубликовано: (2008)

The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability.
по: Scalfari, A, и др.
Опубликовано: (2010)

IDENTIFYING SUITABLE CANDIDATES FOR CLINICAL-TRIALS OF PROGRESSIVE MULTIPLE-SCLEROSIS
по: Weinshenker, B, и др.
Опубликовано: (1993)

Therapeutic trials in multiple sclerosis.
по: Noseworthy, J, и др.
Опубликовано: (1984)

Primary progressive multiple sclerosis: Brain MRI findings
по: Kremenchutzky, M, и др.
Опубликовано: (1999)

No effect of APOE and PVRL2 on the clinical outcome of multiple sclerosis.
по: Ramagopalan, S, и др.
Опубликовано: (2007)

CLINICAL PROGNOSTIC MARKERS IN MULTIPLE-SCLEROSIS
по: Paty, D, и др.
Опубликовано: (1979)

Diagnostic brain MRI findings in primary progressive multiple sclerosis.
по: Kremenchutzky, M, и др.
Опубликовано: (2000)

Surrogate endpoints for EDSS worsening in multiple sclerosis: a meta-analytic approach: measuring disability in relapsing-remitting MS.
по: Ebers, G, и др.
Опубликовано: (2011)

APPLICATIONS OF STUDIES OF THE NATURAL-HISTORY OF MULTIPLE-SCLEROSIS TO THE PLANNING AND INTERPRETATION OF CLINICAL-TRIALS
по: Weinshenker, B, и др.
Опубликовано: (1989)

A comparison of simulated short-term outcomes from multiple sclerosis natural history (NH) data and observed outcomes in a clinical trial (CT)
по: Kremenchutzky, M, и др.
Опубликовано: (2001)

The effectiveness of Natalizumab on MRI outcome measures in patients with relapsing multiple sclerosis
по: Dalton, C, и др.
Опубликовано: (2003)

Decentralised clinical trials in multiple sclerosis research
по: Garjani, A, и др.
Опубликовано: (2022)

EVI5 is a risk gene for multiple sclerosis.
по: Hoppenbrouwers, I, и др.
Опубликовано: (2008)

The impact of blinding on the results of a randomized, placebo-controlled multiple sclerosis clinical trial
по: Nosworthy, J, и др.
Опубликовано: (2001)

The impact of blinding on the results of a randomized, placebo-controlled multiple sclerosis clinical trial.
по: Noseworthy, J, и др.
Опубликовано: (1994)

Maternal transmission of multiple sclerosis in a dutch population.
по: Hoppenbrouwers, I, и др.
Опубликовано: (2008)

The Mayo Clinic-Canadian Cooperative trial of sulfasalazine in active multiple sclerosis.
по: Noseworthy, J, и др.
Опубликовано: (1998)

Life expectancy in patients attending multiple sclerosis clinics.
по: Sadovnick, A, и др.
Опубликовано: (1992)

A referendum on clinical trial research in multiple sclerosis: the opinion of the participants at the Jekyll Island workshop.
по: Noseworthy, J, и др.
Опубликовано: (1989)

The natural history of multiple sclerosis: a geographically based study. 6. Applications to planning and interpretation of clinical therapeutic trials in primary progressive multiple sclerosis.
по: Cottrell, D, и др.
Опубликовано: (1999)

Preventing multiple sclerosis?
по: Ebers, G
Опубликовано: (2001)

Treatment of multiple sclerosis.
по: Ebers, G
Опубликовано: (1994)

The pathogenesis of multiple sclerosis
по: Ebers, G
Опубликовано: (1998)

Preventing multiple sclerosis?
по: Ebers, G
Опубликовано: (2001)

Acceptance of placebo-control trial design by progressive multiple sclerosis patients. The Canadian Cooperative Multiple Sclerosis Study Group.
по: Noseworthy, J, и др.
Опубликовано: (1989)

Cause of death in patients attending multiple sclerosis clinics.
по: Sadovnick, A, и др.
Опубликовано: (1991)

Genome-wide significant risk genes for multiple sclerosis
по: Hoppenbrouwers, I, и др.
Опубликовано: (2009)

Can rate of brain atrophy in multiple sclerosis be explained by clinical and MRI characteristics?
по: Korteweg, T, и др.
Опубликовано: (2009)

Sex ratio of multiple sclerosis and clinical phenotype.
по: Ramagopalan, S, и др.
Опубликовано: (2010)

An open trial of OKT3 in patients with multiple sclerosis.
по: Weinshenker, BG, и др.
Опубликовано: (1991)

Genetics of multiple sclerosis.
по: Sadovnick, A, и др.
Опубликовано: (1995)

Genes for multiple sclerosis.
по: Ramagopalan, S, и др.
Опубликовано: (2008)

OLIGOCLONAL BANDS IN MULTIPLE-SCLEROSIS - CLINICAL-PATHOLOGICAL CORRELATION - REPLY
по: Farrell, M, и др.
Опубликовано: (1986)