Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers
<p><strong>Background:</strong> Primaquine is an 8-aminoquinoline antimalarial. It is the only widely available treatment to prevent relapses of Plasmodium vivax malaria. The 8-aminoquinolines cause dose-dependent haemolysis in glucose-6-phosphate dehydrogenase deficiency (G6PDd)....
| Autors principals: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Idioma: | English |
| Publicat: |
eLife Sciences Publications
2024
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