Synthesis and anti-parasitic activity of dehydrodieugenol B and analogues

This thesis describes the optimisation of a copper-catalysed biaryl ether forming reaction, and its application in the synthesis of the anti-kinetoplastid natural products, isolated from the leaves of Nectandra leucantha

Manylion Llyfryddiaeth
Prif Awdur:	Sear, C
Awduron Eraill:	Anderson, E
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2020
Pynciau:	Chemistry, Organic Chemistry

Eitemau Tebyg

Biological activity and structure–activity relationship of dehydrodieugenol B analogues against visceral leishmaniasis
gan: Amaral, M, et al.
Cyhoeddwyd: (2023)

Synthesis and evaluation of novel chromanone and quinolinone analogues of uniflorol as anti-leishmanial agents
gan: Helena Castro, et al.
Cyhoeddwyd: (2020-03-01)

Synthesis and structure–activity relationship of dehydrodieugenol B neolignans against Trypanosoma cruzi
gan: Sear, CE, et al.
Cyhoeddwyd: (2020)

Dehydrodieugenol B derivatives as antiparasitic agents: synthesis and biological activity against Trypanosoma cruzi
gan: Ferreira, D, et al.
Cyhoeddwyd: (2019)

New reagents and reactions for the synthesis of sulfinates and their aza-analogues
gan: Andrews, JA
Cyhoeddwyd: (2023)

One-pot synthesis of β-N-glycosyl imidazole analogues via a palladium-catalysed decarboxylative allylation
gan: Xiang, Shaohua, et al.
Cyhoeddwyd: (2014)

Synthesis studies towards daphlongeranine B
gan: Kallstrom, JED
Cyhoeddwyd: (2013)

Total synthesis of rubriflordilactone B and pseudo-rubriflordilactone B
gan: Mohammad, M
Cyhoeddwyd: (2018)

Studies towards the total synthesis of an anti-HIV natural product
gan: Guggiari, S
Cyhoeddwyd: (2019)

Synthesis and applications of carbohydrate scaffolds via iminium activation
gan: Seah, Georgina Estelle Kim Kui
Cyhoeddwyd: (2014)

Asymmetric total synthesis of inthomycin c and studies towards the total synthesis of oxazolomycin b
gan: Garcia, S
Cyhoeddwyd: (2017)

Analogues of antibacterial natural products
gan: Heaviside, EA
Cyhoeddwyd: (2012)

Asymmetric synthesis of the loline alkaloids
gan: Linsdall, SM
Cyhoeddwyd: (2019)

Synthesis of taurospongin A and other biologically active natural products
gan: Wu, B
Cyhoeddwyd: (2017)

Synthesis of curvulone B and allahabadolactone, and the development of a diastereoselective Tsuji-Trost cyclisation
gan: Wang, Kongchen
Cyhoeddwyd: (2017)

Synthesis and biological activity of fused tetracyclic Pyrrolo[2,1-c][1,4]benzodiazepines
gan: Joel K. Annor-Gyamfi, et al.
Cyhoeddwyd: (2018-02-01)

Application of new synthetic methodologies to access 2,6-anti-tetrahydropyrans : towards the total synthesis of apicularen A
gan: Chua, Sin Siu
Cyhoeddwyd: (2014)

Studies towards the total synthesis of the heronamide family of natural products
gan: Toma, EC
Cyhoeddwyd: (2021)

Design and synthesis of a bifunctional linker for N-linked glycopeptide synthesis
gan: Lin, Desmond Junjie
Cyhoeddwyd: (2022)

Studies towards the stereoselective synthesis of alkenes
gan: Arif, T
Cyhoeddwyd: (2011)

Hydrogen-bonding motifs for non-covalent synthesis
gan: Pearson, JM
Cyhoeddwyd: (2013)

Recent developments in one-pot stepwise synthesis (OPSS) of small molecules
gan: Xiaoming Ma, et al.
Cyhoeddwyd: (2022-09-01)

Substrate analogue studies on cephalosporin biosynthesis enzymes
gan: Foster, F
Cyhoeddwyd: (2022)

Rhodium catalysed hydroacylation reactions in the synthesis of heterocycles
gan: Ylioja, P
Cyhoeddwyd: (2011)

Silver triflate catalyzed cyclopropyl carbinol rearrangement for benzo[b]oxepine and 2H-chromene synthesis
gan: Chan, Philip Wai Hong, et al.
Cyhoeddwyd: (2015)

Synthesis of 3-amino-2,3-dideoxysugars with their applications and total synthesis of pyridone alkaloids
gan: Ding, Feiqing
Cyhoeddwyd: (2013)

Indian Journal of Chemistry. Section B. Organic & Medical Chemistry.
Cyhoeddwyd: (1980)

Natural product inspired synthesis of cysteine-derived tetramates for antibacterial activity
gan: Zhang, R
Cyhoeddwyd: (2020)

Supramolecular control of synthesis and electronic structure of porphyrin oligomers
gan: Sprafke, J, et al.
Cyhoeddwyd: (2011)

Selective synthesis of meta-phenols from bio-benzoic acids via regulating the adsorption state
gan: Xinze Du, et al.
Cyhoeddwyd: (2023-08-01)

Microwave-assisted rapid and sustainable synthesis of unsymmetrical azo dyes by coupling of nitroarenes with aniline derivatives
gan: Ankit Thakuri, et al.
Cyhoeddwyd: (2022-06-01)

Synthesis and characterization of activated carbons prepared from benzene CVD on zeolite Y
gan: Song, X. H., et al.
Cyhoeddwyd: (2013)

Lewis acid activated electrophilic alcohols as alkylating agents for the stereoselective synthesis of heterocycles
gan: Zhu, Y
Cyhoeddwyd: (2020)

Enantioselective synthesis and reactivity of benzylic fluorides
gan: Blessley, G, et al.
Cyhoeddwyd: (2013)

Synthesis of poly-α/β-peptides with tunable sequence via the copolymerization on N-carboxyanhydride and N-thiocarboxyanhydride
gan: Min Zhou, et al.
Cyhoeddwyd: (2021-10-01)

Palladium- and copper-catalysed heterocycle synthesis
gan: Ball, C
Cyhoeddwyd: (2014)

Synthesis and ultrafast spectroscopy of porphyrin molecular wires
gan: Kendrick, W
Cyhoeddwyd: (2019)

Synthesis and reactivity of [3.1.1]propellane
gan: Frank, N
Cyhoeddwyd: (2022)

Palladium-catalysed enolate arylation in the synthesis of isoquinolines
gan: Gatland, A, et al.
Cyhoeddwyd: (2014)