Biparental inheritance of mitochondrial DNA revisited
Evidence for a biparental mode of mitochondrial DNA (mtDNA) inheritance has been sparse and remains controversial. Recent studies using a range of complementary techniques do not support paternal transmission of mtDNA and highlight the co-amplification of rare, concatenated nuclear mtDNA segments as...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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Nature Research
2021
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| _version_ | 1797050431845695488 |
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| author | Pagnamenta, AT Wei, W Rahman, S Chinnery, PF |
| author_facet | Pagnamenta, AT Wei, W Rahman, S Chinnery, PF |
| author_sort | Pagnamenta, AT |
| collection | OXFORD |
| description | Evidence for a biparental mode of mitochondrial DNA (mtDNA) inheritance has been sparse and remains controversial. Recent studies using a range of complementary techniques do not support paternal transmission of mtDNA and highlight the co-amplification of rare, concatenated nuclear mtDNA segments as a technical artefact that may explain previous observations.
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| first_indexed | 2024-03-06T18:05:03Z |
| format | Journal article |
| id | oxford-uuid:01294a4a-54ff-40a3-88d3-9af4eb684f2d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:05:03Z |
| publishDate | 2021 |
| publisher | Nature Research |
| record_format | dspace |
| spelling | oxford-uuid:01294a4a-54ff-40a3-88d3-9af4eb684f2d2022-03-26T08:33:22ZBiparental inheritance of mitochondrial DNA revisitedJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:01294a4a-54ff-40a3-88d3-9af4eb684f2dEnglishSymplectic ElementsNature Research2021Pagnamenta, ATWei, WRahman, SChinnery, PFEvidence for a biparental mode of mitochondrial DNA (mtDNA) inheritance has been sparse and remains controversial. Recent studies using a range of complementary techniques do not support paternal transmission of mtDNA and highlight the co-amplification of rare, concatenated nuclear mtDNA segments as a technical artefact that may explain previous observations. |
| spellingShingle | Pagnamenta, AT Wei, W Rahman, S Chinnery, PF Biparental inheritance of mitochondrial DNA revisited |
| title | Biparental inheritance of mitochondrial DNA revisited |
| title_full | Biparental inheritance of mitochondrial DNA revisited |
| title_fullStr | Biparental inheritance of mitochondrial DNA revisited |
| title_full_unstemmed | Biparental inheritance of mitochondrial DNA revisited |
| title_short | Biparental inheritance of mitochondrial DNA revisited |
| title_sort | biparental inheritance of mitochondrial dna revisited |
| work_keys_str_mv | AT pagnamentaat biparentalinheritanceofmitochondrialdnarevisited AT weiw biparentalinheritanceofmitochondrialdnarevisited AT rahmans biparentalinheritanceofmitochondrialdnarevisited AT chinnerypf biparentalinheritanceofmitochondrialdnarevisited |