Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates.
Based on structural analysis of the human 2-oxoglutarate (2OG) dependent JMJD2 histone N(ε)-methyl lysyl demethylase family, 3-substituted pyridine 2,4-dicarboxylic acids were identified as potential inhibitors with possible selectivity over other human 2OG oxygenases. Microwave-assisted palladium-c...
| Hoofdauteurs: | , , , , , , |
|---|---|
| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
2011
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Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates.
Gepubliceerd in 2011
Journal article