Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates.
Based on structural analysis of the human 2-oxoglutarate (2OG) dependent JMJD2 histone N(ε)-methyl lysyl demethylase family, 3-substituted pyridine 2,4-dicarboxylic acids were identified as potential inhibitors with possible selectivity over other human 2OG oxygenases. Microwave-assisted palladium-c...
| Main Authors: | , , , , , , |
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| Formato: | Journal article |
| Idioma: | English |
| Publicado: |
2011
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Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates.
Publicado 2011
Journal article