Evaluation of the role of miR-31-dependent reduction in dystrophin and nNOS on atrial-fibrillation-induced electrical remodelling in man

Evaluation of the role of miR-31-dependent reduction in dystrophin and nNOS on atrial-fibrillation-induced electrical remodelling in man

The management of atrial fibrillation remains a challenge. This condition remodels atrial electrical properties, which promote resistance to treatment. Although remodelling has long been a therapeutic target in atrial fibrillation, its causes remain incompletely understood. We aimed to evaluate the...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Reilly, S, Liu, X, Carnicer, R, Rajakumar, T, Sayeed, R, Krasopoulos, G, Verheule, S, Fulga, T, Schotten, U, Casadei, B
Μορφή:	Conference item
Γλώσσα:	English
Έκδοση:	Elsevier 2015

Παρόμοια τεκμήρια

Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase
ανά: Reilly, S, κ.ά.
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Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.
ανά: Reilly, S, κ.ά.
Έκδοση: (2016)

Atrial Fibrillation Causes a Progressive, Time-Dependent Reduction in Myocardial Neuronal NOS in Humans and Goats: Implications for AF-Induced Electrical Remodeling
ανά: Reilly, S, κ.ά.
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Time-dependent regional differences in sources of oxidative stress in atrial fibrillation-induced remodelling
ανά: Reilly, SN, κ.ά.
Έκδοση: (2008)

ATRIAL SOURCES OF REACTIVE OXYGEN SPECIES VARY WITH THE SUBSTRATE AND DURATION OF ATRIAL FIBRILLATION: IMPLICATIONS FOR THE ANTIARRHYTHMIC EFFECT OF STATINS
ανά: Reilly, S, κ.ά.
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Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins
ανά: Reilly, S, κ.ά.
Έκδοση: (2011)

Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins.
ανά: Reilly, S, κ.ά.
Έκδοση: (2011)

Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins.
ανά: Reilly, SN, κ.ά.
Έκδοση: (2011)

Considerations for the Assessment of Substrates, Genetics and Risk Factors in Patients with Atrial Fibrillation
ανά: Dominik Linz, κ.ά.
Έκδοση: (2021-10-01)

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.
ανά: Li, D, κ.ά.
Έκδοση: (2010)

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin
ανά: Li, D, κ.ά.
Έκδοση: (2010)

Time-Dependent and Regional Differences in Myocardial Nitric Oxide-Redox State in Atrial Fibrillation
ανά: Reilly, S, κ.ά.
Έκδοση: (2008)

Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice
ανά: Mighiu, AS, κ.ά.
Έκδοση: (2021)

Streptozotocin-induced diabetes mellitus increases the risk for atrial fibrillation
ανά: Ziberna, K, κ.ά.
Έκδοση: (2016)

Dystrophin R16/17-syntrophin PDZ fusion protein restores sarcolemmal nNOSμ
ανά: Aman Patel, κ.ά.
Έκδοση: (2018-11-01)

Is increased myocardial oxidative stress an early event in the natural history of atrial fibrillation?
ανά: Reilly, S, κ.ά.
Έκδοση: (2007)

BH4 increases nNOS Activity and preserves left ventricular function in diabetes
ανά: Carnicer Hijazo, R, κ.ά.
Έκδοση: (2021)

The Role of Atrial Remodelling in Atrial Fibrillation
ανά: Ignatius Yansen, κ.ά.
Έκδοση: (2013-06-01)

Immune remodeling and atrial fibrillation
ανά: Yajun Yao, κ.ά.
Έκδοση: (2022-07-01)

nNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction
ανά: Dawson, D, κ.ά.
Έκδοση: (2005)

nNOS gene deletion exacerbates pathological left ventricular remodelling and functional deterioration after myocardial infarction
ανά: Dawson, D, κ.ά.
Έκδοση: (2005)

nNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction.
ανά: Dawson, D, κ.ά.
Έκδοση: (2005)

Dystrophin R16/17 protein therapy restores sarcolemmal nNOS in trans and improves muscle perfusion and function
ανά: Junling Zhao, κ.ά.
Έκδοση: (2019-07-01)

Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation
ανά: Carnicer, R, κ.ά.
Έκδοση: (2011)

Molecular Basis of Atrial Nitroso-Redox Imbalance in Permanent Human Atrial Fibrillation
ανά: Reilly, S, κ.ά.
Έκδοση: (2009)

Mapping of atrial fibrillation - basic research and clinical applications
ανά: U Schotten
Έκδοση: (2009-09-01)

Rearrangement of atrial bundle architecture and consequent changes in anisotropy of conduction constitute the 3-dimensional substrate for atrial fibrillation.
ανά: Maesen, B, κ.ά.
Έκδοση: (2013)

Rearrangement of Atrial Bundle Architecture and Consequent Changes in Anisotropy of Conduction Constitute the 3-Dimensional Substrate for Atrial Fibrillation
ανά: Maesen, B, κ.ά.
Έκδοση: (2013)

Neuronal nitric oxide synthase-rescue of dystrophin/utrophin double knockout mice does not require nNOS localization to the cell membrane.
ανά: Michelle Wehling-Henricks, κ.ά.
Έκδοση: (2011-01-01)

Discordant response to exercise training in nnos knockout mice: Differential role of nNOS on exercise performance versus cardiac hypertrophy
ανά: de Bono, J, κ.ά.
Έκδοση: (2007)

Mechanisms of atrial fibrillation
ανά: Wijesurendra, RS, κ.ά.
Έκδοση: (2019)

Atrial matrix remodeling in atrial fibrillation patients with aortic stenosis
ανά: Mariana Fragão-Marques, κ.ά.
Έκδοση: (2020-10-01)

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ανά: Stef Zeemering, κ.ά.
Έκδοση: (2020-10-01)

Different sources of oxidant stress in the early and late stage of atrial fibrillation
ανά: Reilly, SN, κ.ά.
Έκδοση: (2008)

Atrial Electrophysiological Remodeling and Fibrillation in Heart Failure
ανά: Sandeep V. Pandit, κ.ά.
Έκδοση: (2016-10-01)

The Acetylcholine-Activated Potassium Current Inhibitor XAF-1407 Terminates Persistent Atrial Fibrillation in Goats
ανά: Vladimír Sobota, κ.ά.
Έκδοση: (2021-01-01)

Telomere Length Is Associated With Adverse Atrial Remodeling in Patients With Atrial Fibrillation
ανά: Kabita Pradhan, κ.ά.
Έκδοση: (2025-02-01)

Sacubitril/valsartan attenuates atrial structural remodelling in atrial fibrillation patients
ανά: Liu Yang, κ.ά.
Έκδοση: (2022-08-01)

Canagliflozin Suppresses Atrial Remodeling in a Canine Atrial Fibrillation Model
ανά: Ryo Nishinarita, κ.ά.
Έκδοση: (2021-01-01)

Cardiac nNOS regulates myocardial relaxation by stimulating phospholamban phosphorylation
ανά: Zhang, Y, κ.ά.
Έκδοση: (2005)