Label-free, all-optical detection, imaging, and tracking of a single protein.

Optical detection of individual proteins requires fluorescent labeling. Cavity and plasmonic methodologies enhance single molecule signatures in the absence of any labels but have struggled to demonstrate routine and quantitative single protein detection. Here, we used interferometric scattering mic...

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Bibliografiska uppgifter
Huvudupphovsmän: Ortega Arroyo, J, Andrecka, J, Spillane, K, Billington, N, Takagi, Y, Sellers, JR, Kukura, P
Materialtyp: Journal article
Språk:English
Publicerad: American Chemical Society 2014