Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis.
We compared 65 anti-acetylcholine receptor (AChR)-negative myasthenia gravis (MG) patients, including 32 anti-muscle-specific tyrosine kinase (MuSK)-positive (49%) and 33 anti-MuSK-negative (seronegative) (51%) patients, with 161 anti-AChR-positive MG patients. The anti-MuSK-positive group had a hig...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Language: | English |
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2007
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| _version_ | 1797050505481945088 |
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| author | Deymeer, F Gungor-Tuncer, O Yilmaz, V Parman, Y Serdaroglu, P Ozdemir, C Vincent, A Saruhan-Direskeneli, G |
| author_facet | Deymeer, F Gungor-Tuncer, O Yilmaz, V Parman, Y Serdaroglu, P Ozdemir, C Vincent, A Saruhan-Direskeneli, G |
| author_sort | Deymeer, F |
| collection | OXFORD |
| description | We compared 65 anti-acetylcholine receptor (AChR)-negative myasthenia gravis (MG) patients, including 32 anti-muscle-specific tyrosine kinase (MuSK)-positive (49%) and 33 anti-MuSK-negative (seronegative) (51%) patients, with 161 anti-AChR-positive MG patients. The anti-MuSK-positive group had a higher frequency of bulbar involvement and respiratory crises. The seronegative group was in between the anti-MuSK positive and the anti-AChR positive groups, being closer to the latter, with regard to the severity of the disease. At the end of follow-up, the outcome of the anti-MuSK-positive patients was not different from that of the anti-AChR-positive patients, although their maintenance corticosteroid dose was higher. The seronegative patients had better outcome than the other two groups. |
| first_indexed | 2024-03-06T18:06:10Z |
| format | Journal article |
| id | oxford-uuid:017da1c2-c051-4c12-b58f-38ed16cdeb33 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:06:10Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:017da1c2-c051-4c12-b58f-38ed16cdeb332022-03-26T08:35:17ZClinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:017da1c2-c051-4c12-b58f-38ed16cdeb33EnglishSymplectic Elements at Oxford2007Deymeer, FGungor-Tuncer, OYilmaz, VParman, YSerdaroglu, POzdemir, CVincent, ASaruhan-Direskeneli, GWe compared 65 anti-acetylcholine receptor (AChR)-negative myasthenia gravis (MG) patients, including 32 anti-muscle-specific tyrosine kinase (MuSK)-positive (49%) and 33 anti-MuSK-negative (seronegative) (51%) patients, with 161 anti-AChR-positive MG patients. The anti-MuSK-positive group had a higher frequency of bulbar involvement and respiratory crises. The seronegative group was in between the anti-MuSK positive and the anti-AChR positive groups, being closer to the latter, with regard to the severity of the disease. At the end of follow-up, the outcome of the anti-MuSK-positive patients was not different from that of the anti-AChR-positive patients, although their maintenance corticosteroid dose was higher. The seronegative patients had better outcome than the other two groups. |
| spellingShingle | Deymeer, F Gungor-Tuncer, O Yilmaz, V Parman, Y Serdaroglu, P Ozdemir, C Vincent, A Saruhan-Direskeneli, G Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis. |
| title | Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis. |
| title_full | Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis. |
| title_fullStr | Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis. |
| title_full_unstemmed | Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis. |
| title_short | Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis. |
| title_sort | clinical comparison of anti musk vs anti achr positive and seronegative myasthenia gravis |
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