Functional comparison of the endothelial nitric oxide synthase Glu298Asp polymorphic variants in human endothelial cells.

Functional comparison of the endothelial nitric oxide synthase Glu298Asp polymorphic variants in human endothelial cells.

The G894T endothelial nitric oxide synthase (eNOS) polymorphism results in a Glu to Asp substitution at position 298. This position is located externally on the protein and as the regulation of eNOS is dependent on its subcellular localization and interaction with modulatory proteins, we aimed to ad...

Descripció completa

Dades bibliogràfiques
Autors principals:	McDonald, D, Alp, N, Channon, K
Format:	Journal article
Idioma:	English
Publicat:	2004

Ítems similars

Functional assessment of the endothelial nitric oxide synthase Glu298Asp polymorphism
per: McDonald, D, et al.
Publicat: (2002)

Relationship between the G894T polymorphism (Glu298Asp variant) in endothelial nitric oxide synthase and nitric oxide-mediated endothelial function in human atherosclerosis.
per: Guzik, T, et al.
Publicat: (2001)

The Glu298-Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function
per: Leeson, C, et al.
Publicat: (2000)

Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function.
per: Leeson, C, et al.
Publicat: (2002)

The endothelial nitric oxide synthase Glu298Asp polymorphism is not a risk factor for endometriosis in south Indian women.
per: Bhanoori, M, et al.
Publicat: (2008)

Association between the Glu298Asp and T(-786)C polymorphisms of the endothelial nitric oxide synthase gene and respiratory distress in preterm neonates
per: Ercan Sivasli, et al.
Publicat: (2010-04-01)

Endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298asp) and nitric oxide (NO) levels in patients with ST-segment elevation myocardial infarction (STEMI)
per: Mohit Dayal Gupta, et al.
Publicat: (2024-01-01)

Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
per: Alp, N, et al.
Publicat: (2004)

Role of Polymorphisms of Inducible Nitric Oxide Synthase and Endothelial Nitric Oxide Synthase in Idiopathic Environmental Intolerances
per: Chiara De Luca, et al.
Publicat: (2015-01-01)

Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease.
per: Channon, K
Publicat: (2004)

Regulation of endothelial nitric oxide synthase (eNOS) by tetrahydrobiopterin in vascular disease
per: Alp, N, et al.
Publicat: (2004)

Endothelial tetrahydrobiopterin deficiency accelerates atherosclerotic progression by nitric oxide synthase uncoupling
per: Khoo, J, et al.
Publicat: (2005)

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
per: Cai, S, et al.
Publicat: (2005)

Endothelial nitric oxide synthase and heart rate.
per: Herring, N, et al.
Publicat: (2002)

Role of nitric oxide and endothelial NO synthase in carcinogenesis
per: V. P. Deryagina, et al.
Publicat: (2021-07-01)

Reduced levels of tetrahydrobiopterin in diabetic mouse model: Effects on endothelial function and nitric oxide (NO) synthase dimerisation
per: Cai, S, et al.
Publicat: (2004)

POLYMORPHISMS OF ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE AS PREDICTORS OF WOLFF-PARKINSON-WHITE SYNDROME
per: G. V. Matyushin, et al.
Publicat: (2017-11-01)

Genetic Polymorphisms of Endothelial Nitric Oxide Synthase Associated with Hypertension and Blood Homocysteine Levels
per: Chaichanabut C, et al.
Publicat: (2024-04-01)

Determination of Endothelial Nitric Oxide Synthase Gene Polymorphism and Plasma Asymmetric Dimethyl Arginine Concentrations in Patients with Lung Cancer
per: Zafer Bayraktutan, et al.
Publicat: (2020-06-01)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
per: Crabtree, M, et al.
Publicat: (2011)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
per: Crabtree, M, et al.
Publicat: (2011)

Genetic polymorphism on endothelial nitric oxide synthase affects endothelial activation and inflammatory response during the acute phase of myocardial infarction.
per: Antoniades, C, et al.
Publicat: (2005)

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
per: Cai, S, et al.
Publicat: (2002)

Truncated estrogen receptor alpha 46-kDa isoform in human endothelial cells: relationship to acute activation of nitric oxide synthase.
per: Figtree, G, et al.
Publicat: (2003)

Tetrahydrobiopterin Prevents Lung Ischemia/reperfusion-Induced Uncoupling of Endothelial Nitric Oxide Synthase
per: Juni, R, et al.
Publicat: (2012)

Photobiomodulation Inhibits Ischemia-Induced Brain Endothelial Senescence via Endothelial Nitric Oxide Synthase
per: Yu Feng, et al.
Publicat: (2024-05-01)

Relationships between vascular/plasma biopterins and endothelial nitric oxide synthase coupling, endothelial function and inflammation, in human atherosclerosis
per: Antoniades, C, et al.
Publicat: (2008)

Evaluation of Endothelial Nitric Oxide Synthase and Nitric Oxide Levels in Preeclamptic and Normotensive Pregnant Women
per: Rajeev Gandham, et al.
Publicat: (2021-01-01)

Altered plasma versus vascular biopterins in human atherosclerosis reveal relationships between endothelial nitric oxide synthase coupling, endothelial function, and inflammation.
per: Antoniades, C, et al.
Publicat: (2007)

Prevention of hypoxia-induced pulmonary hypertension and vascular remodelling by targeting endothelial tetrahydrobiopterin-dependent nitric oxide synthase regulation
per: Khoo, J, et al.
Publicat: (2005)

Effects of endothelial nitric oxide synthase on mouse arteriovenous fistula hemodynamics
per: Shelly Baltazar, et al.
Publicat: (2023-12-01)

Endothelial nitric oxide synthase single nucleotide polymorphism and left ventricular function in early chronic kidney disease.
per: Sourabh Chand, et al.
Publicat: (2015-01-01)

Integrated redox sensor and effector functions for tetrahydrobiopterin- and glutathionylation-dependent endothelial nitric-oxide synthase uncoupling.
per: Crabtree, M, et al.
Publicat: (2013)

Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.
per: Cai, S, et al.
Publicat: (2005)

Association of Circulating Endothelial Nitric Oxide Synthase Levels with Phosphataemia in Patients on Haemodialysis
per: Leszek Niepolski, et al.
Publicat: (2024-03-01)

Altered plasma vs. vascular biopterins in human atherosclerosis reveal relationships between endothelial nitric oxide synthase coupling, endothelial function and inflammation
per: Antomades, C, et al.
Publicat: (2007)

Evidence for association between endothelial nitric oxide synthase gene polymorphism (G894T) and inflammatory markers: the ATTICA study.
per: Chrysohoou, C, et al.
Publicat: (2004)

The Role of −786T/C Polymorphism in the Endothelial Nitric Oxide Synthase Gene in Males with Clinical and Biochemical Features of the Metabolic Syndrome
per: Blazej Misiak, et al.
Publicat: (2011-01-01)

PROGNOSTIC SIGNIFICANCE OF THE VNTR POLYMORPHISM INTRON 4 OF THE GENE OF NITRIC OXIDE ENDOTHELIAL SYNTHASE IN CHRONIC HEART FAILURE PATIENTS
per: E. A. Polunina, et al.
Publicat: (2018-02-01)

Endothelial nitric oxide synthase gene (T786C and G894T) polymorphisms in Egyptian patients with type 2 diabetes
per: Omneya Moguib, et al.
Publicat: (2017-12-01)