Fibroblast growth factor 2 drives changes in gene expression following injury to murine cartilage in vitro and in vivo.
OBJECTIVE: The articular cartilage is known to be highly mechanosensitive, and a number of mechanosensing mechanisms have been proposed as mediators of the cellular responses to altered mechanical load. These pathways are likely to be important in tissue homeostasis as well as in the pathogenesis of...
Main Authors: | Chong, K, Chanalaris, A, Burleigh, A, Jin, H, Watt, F, Saklatvala, J, Vincent, T |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2013
|
Similar Items
-
Pathogenic protease expression in murine OA is critically dependent upon mechanical joint loading
by: Burleigh, A, et al.
Published: (2012) -
CARTILAGE INJURY REGULATES NERVE GROWTH FACTOR (NGF) IN VTTRO AND IN VIVO AND DRIVES PAINFUL BEHAVIOUR IN MURINE OA
by: Driscoll, C, et al.
Published: (2014) -
Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo.
by: Burleigh, A, et al.
Published: (2012) -
MECHANICAL LOAD DRIVES INFLAMMATORY GENE EXPRESSION AND DISEASE IN MURINE OA
by: Burleigh, A, et al.
Published: (2010) -
The dependence of FGF2 on murine cartilage injury responses
by: Chong, K, et al.
Published: (2011)