Characterization of UHRF2 (RNF107) as a novel sensor for DNA ICLs in the Fanconi Anemia Pathway
<p>The Fanconi Anemia (FA) pathway is important for repairing interstrand crosslinks (ICLs) between the Watson-Crick strands of the DNA helix. An initial and essential stage in the repair process is the detection of the ICL. In a previous study, UHRF1 was identified as an ICL sensor in humans...
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| Format: | Thesis |
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2017
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