Characterization of UHRF2 (RNF107) as a novel sensor for DNA ICLs in the Fanconi Anemia Pathway

<p>The Fanconi Anemia (FA) pathway is important for repairing interstrand crosslinks (ICLs) between the Watson-Crick strands of the DNA helix. An initial and essential stage in the repair process is the detection of the ICL. In a previous study, UHRF1 was identified as an ICL sensor in humans...

Täydet tiedot

Bibliografiset tiedot
Päätekijä: Motnenko, A
Muut tekijät: Cohn, MA
Aineistotyyppi: Opinnäyte
Julkaistu: 2017