Frequency of germline hereditary non-polyposis colorectal cancer gene mutations in patients with multiple or early onset colorectal adenomas.

Frequency of germline hereditary non-polyposis colorectal cancer gene mutations in patients with multiple or early onset colorectal adenomas.

BACKGROUND: The hereditary non-polyposis colorectal cancer (HNPCC) syndrome is caused by germline mutations in mismatch repair genes and predisposes individuals to cancers of the colon and other specific sites. On theoretical grounds, it is expected that patients with HNPCC also develop more colorec...

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Detalles Bibliográficos
Autores principales: Beck, N, Tomlinson, I, Homfray, T, Frayling, I, Hodgson, S, Bodmer, W
Formato: Journal article
Lenguaje:English
Publicado: 1997

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