Studies on the transformation of nitrosugars into branched chain iminosugars. Part II: Synthesis of (3R,4R,5R,6S)-2,2-bis(hydroxymethyl)azepane-3,4,5,6-tetraol
The first stereocontrolled synthesis of (3R,4R,5R,6S)-2,2-bis-(hydroxymethyl)azepane-3,4,5,6-tetraol is described herein. The method involves a novel double Henry reaction of the 3,5-di-O-benzyl-6-deoxy-1,2-O-isopropylidene-6-nitro-α-d-glucofuranose with formaldehyde followed by a reductive ring clo...
Бүрэн тодорхойлолт
Номзүйн дэлгэрэнгүй
| Үндсэн зохиолчид: |
Otero, J,
Estevez, A,
Soengas, R,
Estevez, J,
Nash, R,
Fleet, G,
Estevez, R |
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| Формат: | Journal article
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| Хэл сонгох: | English |
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| Хэвлэсэн: |
2008
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