Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions.
We have determined Y-chromosomal DNA haplotypes in 73 infertile European males carrying Y microdeletions and compared them with the haplotypes of 299 infertile males lacking microdeletions. Chromosomes were typed with a set of 11 binary Y markers, which identified 8 haplogroups in the sample. Haplog...
Main Authors: | , , , , , , , , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2000
|
_version_ | 1797050577199300608 |
---|---|
author | Paracchini, S Stuppia, L Gatta, V Palka, G Moro, E Foresta, C Mengua, L Oliva, R Ballescà, J Kremer, J van Golde, R Tuerlings, J Hargreave, T Ross, A Cooke, H Huellen, K Vogt, P Tyler-Smith, C |
author_facet | Paracchini, S Stuppia, L Gatta, V Palka, G Moro, E Foresta, C Mengua, L Oliva, R Ballescà, J Kremer, J van Golde, R Tuerlings, J Hargreave, T Ross, A Cooke, H Huellen, K Vogt, P Tyler-Smith, C |
author_sort | Paracchini, S |
collection | OXFORD |
description | We have determined Y-chromosomal DNA haplotypes in 73 infertile European males carrying Y microdeletions and compared them with the haplotypes of 299 infertile males lacking microdeletions. Chromosomes were typed with a set of 11 binary Y markers, which identified 8 haplogroups in the sample. Haplogroup frequencies were compared between 3 microdeletion classes and the non-deleted infertile males. Deletions arise on many different haplotypic backgrounds. No statistically significant differences in frequency were seen, although the small number of AZFa deletions lay predominantly on one branch of the Y haplotype tree. |
first_indexed | 2024-03-06T18:07:13Z |
format | Journal article |
id | oxford-uuid:01d5030f-ec6a-4240-a31d-673757e58f93 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T18:07:13Z |
publishDate | 2000 |
record_format | dspace |
spelling | oxford-uuid:01d5030f-ec6a-4240-a31d-673757e58f932022-03-26T08:37:10ZY-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:01d5030f-ec6a-4240-a31d-673757e58f93EnglishSymplectic Elements at Oxford2000Paracchini, SStuppia, LGatta, VPalka, GMoro, EForesta, CMengua, LOliva, RBallescà, JKremer, Jvan Golde, RTuerlings, JHargreave, TRoss, ACooke, HHuellen, KVogt, PTyler-Smith, CWe have determined Y-chromosomal DNA haplotypes in 73 infertile European males carrying Y microdeletions and compared them with the haplotypes of 299 infertile males lacking microdeletions. Chromosomes were typed with a set of 11 binary Y markers, which identified 8 haplogroups in the sample. Haplogroup frequencies were compared between 3 microdeletion classes and the non-deleted infertile males. Deletions arise on many different haplotypic backgrounds. No statistically significant differences in frequency were seen, although the small number of AZFa deletions lay predominantly on one branch of the Y haplotype tree. |
spellingShingle | Paracchini, S Stuppia, L Gatta, V Palka, G Moro, E Foresta, C Mengua, L Oliva, R Ballescà, J Kremer, J van Golde, R Tuerlings, J Hargreave, T Ross, A Cooke, H Huellen, K Vogt, P Tyler-Smith, C Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions. |
title | Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions. |
title_full | Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions. |
title_fullStr | Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions. |
title_full_unstemmed | Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions. |
title_short | Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions. |
title_sort | y chromosomal dna haplotypes in infertile european males carrying y microdeletions |
work_keys_str_mv | AT paracchinis ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT stuppial ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT gattav ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT palkag ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT moroe ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT forestac ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT mengual ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT olivar ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT ballescaj ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT kremerj ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT vangolder ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT tuerlingsj ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT hargreavet ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT rossa ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT cookeh ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT huellenk ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT vogtp ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions AT tylersmithc ychromosomaldnahaplotypesininfertileeuropeanmalescarryingymicrodeletions |