Optimization of protocols for derivation of mouse embryonic stem cell lines from refractory strains, including the non obese diabetic mouse.
The derivation of pluripotent embryonic stem cells (ESCs) from a variety of genetic backgrounds remains a desirable objective in the generation of mice functionally deficient in genes of interest and the modeling of human disease. Nevertheless, disparity in the ease with which different strains of m...
Hlavní autoři: | Davies, T, Fairchild, P |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2012
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