TNFα inhibitors reduce bone loss in rheumatoid arthritis independent of clinical response by reducing osteoclast precursors and IL-20

<p><strong>Objectives</strong></p> <p>About half of RA patients treated with TNFα inhibitors either do not respond or lose their initial therapeutic response over time. The clinical response is measured by reduction in DAS28, which primarily reflects inflammation. Howev...

Full description

Bibliographic Details
Main Authors: Al-Bogami, M, Bystrom, J, Clanchy, F, Taher, TE, Mangat, P, Williams, RO, Jawad, AS, Mageed, RA
Format: Journal article
Language:English
Published: Oxford University Press 2020