Model Description Language (MDL): A Standard for Modeling and Simulation

Recent work on Model Informed Drug Discovery and Development (MID3) has noted the need for clarity in model description used in quantitative disciplines such as pharmacology and statistics.1-3 Currently, models are encoded in a variety of computer languages and are shared through publications that r...

Full description

Bibliographic Details
Main Authors: Smith, MK, Moodie, SL, Bizzotto, R, Blaudez. E, Borella, E, Carrara, L, Chan, P, Chenel, M, Comets, E, Gieschke, R, Harling, K, Harnisch, L, Hartung, N, Hooker, AC, Karlsson, MO, Kaye, R, Kloft, C, Kokash, N, Lavielle, M, Lestini, G, Magni, P, Mari, A, Mentré, F, Muselle, C, Nordgren, R, Nyberg, HB, Parra-Guillén, ZP, Pasotti, L, Rode-Kristensen, N, Sardu, ML, Smith, GR, Swat, MJ, Terranova, N, Yngman, G, Yvon, F, Holford, N, DDMoRe consortium
Format: Journal article
Language:English
Published: Wiley 2017
Description
Summary:Recent work on Model Informed Drug Discovery and Development (MID3) has noted the need for clarity in model description used in quantitative disciplines such as pharmacology and statistics.1-3 Currently, models are encoded in a variety of computer languages and are shared through publications that rarely include original code and generally lack reproducibility. The DDMoRe Model Description Language (MDL) has been developed primarily as a language standard to facilitate sharing knowledge and understanding of models.