Manipulation of indoleamine 2,3-dioxygenase (IDO) for clinical transplantation: promises and challenges.

Manipulation of indoleamine 2,3-dioxygenase (IDO) for clinical transplantation: promises and challenges.

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BACKGROUND: Since the discovery that indoleamine 2,3-dioxygenase (IDO) is a modulator for maintenance of fetomaternal immuno-privilege state, it has been implicated in tumour tolerance, autoimmune diseases and asthma. IDO is an IFN-gamma-inducible, intracellular enzyme that catalyzes the initial an...

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Bibliographic Details
Main Authors:	Quan, J, Tan, P, MacDonald, A, Friend, P
Format:	Journal article
Language:	English
Published:	2008

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