Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults
Accumulating evidence has shown that poor oral hygiene is associated with increased risk of cardiometabolic diseases in Western populations. However, its relevance about the relationships in Chinese adults remains unclear. The China Kadoorie Biobank enrolled 512 715 adults aged 30-79 years in China...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Wiley
2021
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| _version_ | 1826307912238104576 |
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| author | Zhuang, Z Gao, M Lv, J Yang, L Du, H Chen, Y Chen, Z |
| author2 | China Kadoorie Biobank (CKB) Collaborative Group |
| author_facet | China Kadoorie Biobank (CKB) Collaborative Group Zhuang, Z Gao, M Lv, J Yang, L Du, H Chen, Y Chen, Z |
| author_sort | Zhuang, Z |
| collection | OXFORD |
| description | Accumulating evidence has shown that poor oral hygiene is associated with increased risk of cardiometabolic diseases in Western populations. However, its relevance about the relationships in Chinese adults remains unclear. The China Kadoorie Biobank enrolled 512 715 adults aged 30-79 years in China during 2004-2008. Cox regression was used to estimate adjusted hazard ratios (HRs) for each disease associated with measures of oral hygiene. Overall 9.3% of the participants reported rarely or never brushing teeth at baseline. Participants who rarely or never brushed teeth had adjusted HR of 1.12 (95% CI: 1.09, 1.15) for MVE, with similar HRs for stroke (1.08, 1.05-1.12), intracerebral haemorrhage (1.18, 1.11-1.26) and pulmonary heart disease (1.22, 1.13-1.32) compared with those who brushed teeth regularly. Those who did not brush teeth also had increased risk of cancer (1.09, 1.04-1.14), chronic obstructive pulmonary disease (COPD) (1.12, 1.05-1.20), liver cirrhosis (1.25, 1.09-1.44) and all-cause death (1.25, 1.21-1.28) but not type 2 diabetes (0.94, 0.86-1.03) and chronic kidney disease (0.98, 0.81-1.18). Among Chinese adults, we found that poor oral hygiene is associated with higher risks of major vascular disease, cancer, COPD, liver cirrhosis and all-cause deaths, but not type 2 diabetes and chronic kidney disease. |
| first_indexed | 2024-03-07T07:10:09Z |
| format | Journal article |
| id | oxford-uuid:023ed478-6d72-4c5d-b61f-0dcfc16acbf8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:10:09Z |
| publishDate | 2021 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:023ed478-6d72-4c5d-b61f-0dcfc16acbf82022-06-21T08:53:52ZAssociations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adultsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:023ed478-6d72-4c5d-b61f-0dcfc16acbf8EnglishSymplectic ElementsWiley2021Zhuang, ZGao, MLv, JYang, LDu, HChen, YChen, ZChina Kadoorie Biobank (CKB) Collaborative GroupAccumulating evidence has shown that poor oral hygiene is associated with increased risk of cardiometabolic diseases in Western populations. However, its relevance about the relationships in Chinese adults remains unclear. The China Kadoorie Biobank enrolled 512 715 adults aged 30-79 years in China during 2004-2008. Cox regression was used to estimate adjusted hazard ratios (HRs) for each disease associated with measures of oral hygiene. Overall 9.3% of the participants reported rarely or never brushing teeth at baseline. Participants who rarely or never brushed teeth had adjusted HR of 1.12 (95% CI: 1.09, 1.15) for MVE, with similar HRs for stroke (1.08, 1.05-1.12), intracerebral haemorrhage (1.18, 1.11-1.26) and pulmonary heart disease (1.22, 1.13-1.32) compared with those who brushed teeth regularly. Those who did not brush teeth also had increased risk of cancer (1.09, 1.04-1.14), chronic obstructive pulmonary disease (COPD) (1.12, 1.05-1.20), liver cirrhosis (1.25, 1.09-1.44) and all-cause death (1.25, 1.21-1.28) but not type 2 diabetes (0.94, 0.86-1.03) and chronic kidney disease (0.98, 0.81-1.18). Among Chinese adults, we found that poor oral hygiene is associated with higher risks of major vascular disease, cancer, COPD, liver cirrhosis and all-cause deaths, but not type 2 diabetes and chronic kidney disease. |
| spellingShingle | Zhuang, Z Gao, M Lv, J Yang, L Du, H Chen, Y Chen, Z Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults |
| title | Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults |
| title_full | Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults |
| title_fullStr | Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults |
| title_full_unstemmed | Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults |
| title_short | Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults |
| title_sort | associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in chinese adults |
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