Evolutionary genetics: what is driving male mutation?
In mammals, most new mutations occur in males. But a study of the evolution of a human X to Y chromosomal translocation has revealed a sex bias much lower than previous estimates. Patterns of substitution suggest that differential methylation between male and female germ lines is a key determinant o...
Main Author: | McVean, G |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2000
|
Similar Items
-
Nonhuman genetics. Strong male bias drives germline mutation in chimpanzees.
by: Venn, O, et al.
Published: (2014) -
What drives recombination hotspots to repeat DNA in humans?
by: McVean, G
Published: (2010) -
The influence of mutation, recombination, population history, and selection on patterns of genetic diversity in Neisseria meningitidis.
by: Jolley, K, et al.
Published: (2005) -
Estimating recombination rates from population-genetic data.
by: Stumpf, M, et al.
Published: (2003) -
Estimating recombination rates from genetic variation in humans.
by: Auton, A, et al.
Published: (2012)