MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy
MLP (muscle LIM protein)-deficient mice count among the first mouse models for dilated cardiomyopathy (DCM), yet the exact role of MLP in cardiac signalling processes is still enigmatic. Elevated PKCasignalling activity is known to be an important contributor to heart failure. Here we show that MLP...
Main Authors: | Gehmlich, K, Lange, S, Lun, A, Blondelle, J, Hooper, C, Dalton, N, Alvarez, E, Zhang, X, Bang, M, Abassi, Y, dos Remedios, C, Peterson, K, Chen, J, Ehler, E |
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Format: | Journal article |
Published: |
Nature Publishing Group: Nature Communications
2016
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