MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy

MLP (muscle LIM protein)-deficient mice count among the first mouse models for dilated cardiomyopathy (DCM), yet the exact role of MLP in cardiac signalling processes is still enigmatic. Elevated PKCasignalling activity is known to be an important contributor to heart failure. Here we show that MLP...

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Dettagli Bibliografici
Autori principali: Gehmlich, K, Lange, S, Lun, A, Blondelle, J, Hooper, C, Dalton, N, Alvarez, E, Zhang, X, Bang, M, Abassi, Y, dos Remedios, C, Peterson, K, Chen, J, Ehler, E
Natura: Journal article
Pubblicazione: Nature Publishing Group: Nature Communications 2016