Variable var transition rates underlie antigenic variation in malaria.

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is expressed on the surface of infected erythrocytes where it plays a central role in both infected erythrocytes cytoadhesion and immune evasion. Switches in clonal expression of PfEMP1 result in antigenic variation that facilitates long-...

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Main Authors: Horrocks, P, Pinches, R, Christodoulou, Z, Kyes, SA, Newbold, C
格式: Journal article
语言:English
出版: 2004