Insights into biochemical and genetical basis of glucokinase activation from naturally occuring hypoglycaemia mutations

Eitemau Tebyg

• Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations.
  gan: Gloyn, A, et al.
  Cyhoeddwyd: (2003)
• Gene duplications resulting in over expression of glucokinase are not a common cause of hypoglycaemia of infancy in humans.
  gan: van de Bunt, M, et al.
  Cyhoeddwyd: (2008)
• Naturally occurring glucokinase mutations are associated with defects in posttranslational S-nitrosylation.
  gan: Ding, S, et al.
  Cyhoeddwyd: (2010)
• Familial persistent hyperinsulinaemic hypoglycaemia of infancy due to a novel glucokinase (GCK) activating mutation G68V
  gan: Gloyn, A, et al.
  Cyhoeddwyd: (2006)
• Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young.
  gan: Gloyn, A, et al.
  Cyhoeddwyd: (2005)