Insights into biochemical and genetical basis of glucokinase activation from naturally occuring hypoglycaemia mutations

Geahča maid

• Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations.
  Dahkki: Gloyn, A, et al.
  Almmustuhtton: (2003)
• Gene duplications resulting in over expression of glucokinase are not a common cause of hypoglycaemia of infancy in humans.
  Dahkki: van de Bunt, M, et al.
  Almmustuhtton: (2008)
• Naturally occurring glucokinase mutations are associated with defects in posttranslational S-nitrosylation.
  Dahkki: Ding, S, et al.
  Almmustuhtton: (2010)
• Familial persistent hyperinsulinaemic hypoglycaemia of infancy due to a novel glucokinase (GCK) activating mutation G68V
  Dahkki: Gloyn, A, et al.
  Almmustuhtton: (2006)
• Phenotypic heterogeneity in a family with a novel activating glucokinase (GCK) mutation (G68V) causing familial persistent hyperinsulinaemic hypoglycaemia of infancy
  Dahkki: Gloyn, A, et al.
  Almmustuhtton: (2007)