IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn's and Colitis
An alliance of clinicians, academics, research nurses, funders, coordinators, programmers and, most importantly, patients has come together in the UK to deliver a powerful new platform to accelerate Crohn’s and Colitis research—the inflammatory bowel disease (IBD) BioResource. As part of the Nationa...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Journal article |
| Language: | English |
| Published: |
BMJ
2019
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| _version_ | 1797050806465200128 |
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| author | Parkes, M IBD BioResource Investigators |
| author2 | Jostins-Dean, L |
| author_facet | Jostins-Dean, L Parkes, M IBD BioResource Investigators |
| author_sort | Parkes, M |
| collection | OXFORD |
| description | An alliance of clinicians, academics, research nurses, funders, coordinators, programmers and, most importantly, patients has come together in the UK to deliver a powerful new platform to accelerate Crohn’s and Colitis research—the inflammatory bowel disease (IBD) BioResource. As part of the National Institute for Health Research (NIHR) BioResource for translational research, 25 000 patients in over 90 hospitals UK-wide have signed up since we launched in January 2016 (figure 1). All have detailed phenotypes databased including Montreal classification,1 treatment response history (updated annually), surgical history and comorbidities (see IBD BioResource panel descriptive, Clinical data collection sheet and Health and Lifestyle questionnaire). Serum, plasma and DNA samples are banked; and genome-wide genetic profiling undertaken. Participants’ data and samples can be studied, and they themselves surveyed or recalled for resampling or downstream studies (see figure 2). Critically, such studies can be led by any UK or overseas investigator whether from the worlds of clinical research, pharmacovigilance, science or industry. |
| first_indexed | 2024-03-06T18:10:39Z |
| format | Journal article |
| id | oxford-uuid:02e6e686-231a-489c-bd96-33882e2ab1f8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:10:39Z |
| publishDate | 2019 |
| publisher | BMJ |
| record_format | dspace |
| spelling | oxford-uuid:02e6e686-231a-489c-bd96-33882e2ab1f82022-03-26T08:43:23ZIBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn's and ColitisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:02e6e686-231a-489c-bd96-33882e2ab1f8EnglishSymplectic ElementsBMJ2019Parkes, MIBD BioResource InvestigatorsJostins-Dean, LAn alliance of clinicians, academics, research nurses, funders, coordinators, programmers and, most importantly, patients has come together in the UK to deliver a powerful new platform to accelerate Crohn’s and Colitis research—the inflammatory bowel disease (IBD) BioResource. As part of the National Institute for Health Research (NIHR) BioResource for translational research, 25 000 patients in over 90 hospitals UK-wide have signed up since we launched in January 2016 (figure 1). All have detailed phenotypes databased including Montreal classification,1 treatment response history (updated annually), surgical history and comorbidities (see IBD BioResource panel descriptive, Clinical data collection sheet and Health and Lifestyle questionnaire). Serum, plasma and DNA samples are banked; and genome-wide genetic profiling undertaken. Participants’ data and samples can be studied, and they themselves surveyed or recalled for resampling or downstream studies (see figure 2). Critically, such studies can be led by any UK or overseas investigator whether from the worlds of clinical research, pharmacovigilance, science or industry. |
| spellingShingle | Parkes, M IBD BioResource Investigators IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn's and Colitis |
| title | IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn's and Colitis |
| title_full | IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn's and Colitis |
| title_fullStr | IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn's and Colitis |
| title_full_unstemmed | IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn's and Colitis |
| title_short | IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn's and Colitis |
| title_sort | ibd bioresource an open access platform of 25 000 patients to accelerate research in crohn s and colitis |
| work_keys_str_mv | AT parkesm ibdbioresourceanopenaccessplatformof25000patientstoaccelerateresearchincrohnsandcolitis AT ibdbioresourceinvestigators ibdbioresourceanopenaccessplatformof25000patientstoaccelerateresearchincrohnsandcolitis |