TNF receptor p55 mediates peripheral cytotoxic T cell deletion.
Antigen driven lymphocyte expansion is limited by cell death in peripheral lymphoid tissues avoiding overwhelming immune responses and autoimmunity. Signals associated with ligation of Fas can lead to lymphocyte apoptosis, but further, Fas-independent mechanisms have been postulated. Recent in vitro...
Main Authors: | Speiser, D, Sebzda, E, Ohteki, T, Bachmann, M, Mak, T, Ohashi, P |
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Format: | Journal article |
Language: | English |
Published: |
1996
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